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Article

Trans-activation of mutant follicle-stimulating hormone receptors selectively generates only one of two hormone signals.

Molecular endocrinology (Baltimore, Md.) - 1 Apr 2004

Ji Inhae, Lee ChangWoo, Jeoung MyoungKun, Koo YongBum, Sievert Gail A, Ji Tae H

Abstract excerpt

Previously, we reported that a liganded LH receptor (LHR) is capable of activating itself (cis-activation) and other nonliganded LHRs to induce cAMP (trans-activation). Trans-activation of the LHR raises two crucial questions. Is trans-activation unique to LHR or common to other G protein-coupled receptors? Does trans-activation stimulate phospholipase Cbeta as it does adenylyl cyclase? To address these...

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Source

Identifiers

PMID: 14726491
DOI: 10.1210/me.2003-0443

Genes

FSHR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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