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In Vivo and In Vitro Impact of Carbohydrate Variation on Human Follicle-Stimulating Hormone Function

9 May 2018

Abstract excerpt

Human FSH exhibits both macro- and micro-heterogeneity in its carbohydrate moieties. Macroheterogeneity results in three physiologically relevant FSH subunit variants that possess a single N-linked glycan at either one of the two L1 loop glycosylation sites, or both glycans. Microheterogeneity is characterized by 80 to over 100 unique oligosaccharide structures attached to each of the 3 to 4 occupied...

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PMID: 29867757
DOI: 10.3389/fendo.2018.00216

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