Article
Tumor suppressor and immediate early transcription factor genes in non-small cell lung cancer.
Chest - 1 Dec 1994
Levin W J, Casey G, Ramos J C, Arboleda M J, Reissmann P T, Slamon D J
Abstract excerpt
Non-small lung cancer (NSCLC) is a disease that exhibits multiple genetic lesions. Lung Cancer Study Group (LCSG) 871 was designed to analyze this group of malignancies for alterations in growth factors and/or their receptors, oncogenes, tumor suppressor genes, and immediate early transcription factor genes. Immunohistochemical analysis showed that 32% of evaluable cases studied contained absent or abnormal Rb...
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