Altered retinoblastoma protein expression and prognosis in early-stage non-small-cell lung carcinoma.

doi:10.1093/jnci/86.9.695

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Article

Altered retinoblastoma protein expression and prognosis in early-stage non-small-cell lung carcinoma.

Journal of the National Cancer Institute - 4 May 1994

Xu H J, Quinlan D C, Davidson A G, Hu S X, Summers C L, Li J, Benedict W F

Abstract excerpt

BACKGROUND: Altered retinoblastoma (RB [also known as RB1]) gene expression was initially found in a small cohort study to occur in five (22%) of 23 patients with primary stage I and II non-small-cell lung carcinomas (NSCLCs). Putative mutation of the p53 gene (also known as TP53) has also been f...

Topics

Adenocarcinoma
Adult
Aged
Carcinoma, Adenosquamous
Carcinoma, Non-Small-Cell Lung
Carcinoma, Squamous Cell
Female
Gene Expression Regulation, Neoplastic
Genes, Retinoblastoma
Genes, p53
Humans
Immunohistochemistry

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Lung Neoplasms

Male

Middle Aged

Multivariate Analysis

Mutation

Neoplasm Staging

Source

Open in PubMed

Identifiers

PMID: 8158700
DOI: 10.1093/jnci/86.9.695

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8158700-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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