Article
The tumor necrosis factor beta * 1 allele is linked significantly to HLA-DR8 in Koreans with atrophic autoimmune thyroiditis who are positive for thyrotropin receptor blocking antibody.
Journal of Korean medical science - 1 Apr 1994
Chung J H, Cho B Y, Lee H K, Kim T G, Han H, Koh C S
Abstract excerpt
The localization and functional characteristics of tumor necrosis factor(TNF) beta gene raise the possibility that it may be involved in the susceptibility to autoimmune thyroid diseases. To investigate whether a TNF beta gene polymorphism is associated with autoimmune thyroiditis, we analyzed th...
Topics
- Alleles
- Genetic Linkage
- HLA-DR Antigens
- Humans
- Korea
- Lymphotoxin-alpha
- Polymorphism, Genetic
- Receptors, Thyrotropin
- Thyroiditis, Autoimmune