Article
A strong association between thyrotropin receptor-blocking antibody-positive atrophic autoimmune thyroiditis and HLA-DR8 and HLA-DQB1*0302 in Koreans.
The Journal of clinical endocrinology and metabolism - 1 Sept 1993
Cho B Y, Chung J H, Shong Y K, Chang Y B, Han H, Lee J B, Lee H K, Koh C S
Abstract excerpt
We investigated whether the associations between HLA alleles of patients with autoimmune hypothyroidism varied according to the presence or absence of TSH receptor-blocking antibody (TRBab). We analyzed the HLA-A, -B, -C, and -DR antigens by serotyping and the DQA1 and DQB1 genes using both enzymatic DNA amplification and sequence-specific oligonucleotide hybridizations. The patient population consisted of 47...
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