[The relevance of tumor necrosis factor-alpha gene-863C/A polymorphism with thyroid-associated ophthalmopathy].

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Article

[The relevance of tumor necrosis factor-alpha gene-863C/A polymorphism with thyroid-associated ophthalmopathy].

[Zhonghua yan ke za zhi] Chinese journal of ophthalmology - 1 Sept 2005

Yan Sheng-li, Wang Ying-xue

Abstract excerpt

OBJECTIVE: To investigate the relevance of tumor necrosis factor-alpha (TNF-alpha) gene -863C/A polymorphism with thyroid-associated ophthalmopathy (TAO). METHODS: TNF-alpha gene polymorphism at position -863 was determined by PCR-RFLP in 76 normal people, 54 patients with TAO and 60 patients with autoimmune thyroid disease (AITD) who had no ophthalmopathy. All the subjects were collected from July 2002 to...

Topics

Adult
Chi-Square Distribution
Female
Gene Frequency
Genotype
Graves Ophthalmopathy
Humans
Male
Middle Aged
Polymorphism, Single Nucleotide
Sex Factors
Tumor Necrosis Factor-alpha

Source

Open in PubMed

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PMID: 16191343

Genes

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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