Article
Repressor mutations in the marRAB operon that activate oxidative stress genes and multiple antibiotic resistance in Escherichia coli.
Journal of bacteriology - 1 Jan 1994
Ariza R R, Cohen S P, Bachhawat N, Levy S B, Demple B
Abstract excerpt
Resistance to multiple antibiotics and certain oxidative stress compounds was conferred by three independently selected mutations (marR1, soxQ1, and cfxB1) that mapped to 34 min on the Escherichia coli chromosome. Mutations at this locus can activate the marRAB operon, in which marR encodes a put...
Topics
- Adaptation, Physiological
- Amino Acid Sequence
- Bacterial Proteins
- Base Sequence
- DNA-Binding Proteins
- Drug Resistance, Microbial
- Escherichia coli
- Escherichia coli Proteins
- Gene Expression Regulation, Bacterial
- Genes, Bacterial
- Genetic Complementation Test