Article
marA, a regulated locus which controls expression of chromosomal multiple antibiotic resistance in Escherichia coli.
Journal of bacteriology - 1 Sept 1991
Hächler H, Cohen S P, Levy S B
Abstract excerpt
Stable chromosomal multiple-antibiotic-resistant (Mar) mutants of Escherichia coli, derived by exposing susceptible cells to low concentrations of tetracycline or chloramphenicol, express cross-resistance to structurally unrelated antibiotics. The entire resistance phenotype is reversed to susceptibility by insertion of transposon Tn5 into a locus, designated marA, near 34 min on the chromosome (A. M. George and...
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