Article
marA, a regulated locus which controls expression of chromosomal multiple antibiotic resistance in Escherichia coli.
Journal of bacteriology - 1 Sept 1991
Hächler H, Cohen S P, Levy S B
Abstract excerpt
Stable chromosomal multiple-antibiotic-resistant (Mar) mutants of Escherichia coli, derived by exposing susceptible cells to low concentrations of tetracycline or chloramphenicol, express cross-resistance to structurally unrelated antibiotics. The entire resistance phenotype is reversed to suscep...
Topics
- Autoradiography
- Chromosome Mapping
- Chromosomes, Bacterial
- Cloning, Molecular
- DNA, Bacterial
- Drug Resistance, Microbial
- Escherichia coli
- Gene Expression Regulation, Bacterial
- Genes, Bacterial
- Mutation
- Nucleic Acid Hybridization
- Phenotype
- RNA, Bacterial
- Restriction Mapping
- Transcription, Genetic