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Article

Molecular modeling to predict the structural and biological effects of mutations in a highly conserved histone mRNA loop sequence.

Journal of biomolecular structure & dynamics - 1 Jun 1992

Gabb H A, Harris M E, Pandey N B, Marzluff W F, Harvey S C

Abstract excerpt

The 3'-end of histone mRNAs contains a highly conserved sequence motif which is believed to form a 6 base pair stem and a 4 base loop. These sequences are involved in both the efficiency of 3'-end formation and stability of the mature histone mRNA. We have modeled four stem basepairs and the loop portion of this structure using the wildtype sequences and several mutant sequences. A structure for the wildtype...

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Identifiers

PMID: 1637506
DOI: 10.1080/07391102.1992.10507983

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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