Article
Role of hns in the virulence phenotype of pathogenic salmonellae.
Molecular microbiology - 1 Jul 1994
Harrison J A, Pickard D, Higgins C F, Khan A, Chatfield S N, Ali T, Dorman C J, Hormaeche C E, Dougan G
Abstract excerpt
A TnphoA-generated mutant C5060, attenuated for virulence, was derived from the mouse-virulent Salmonella typhimurium strain C5. This mutation, designated hns-112::TnphoA, harbours the transposon in the 3' end of hns, with the alkaline phosphatase open reading frame in the opposite orientation to that of hns. Bacterial strains harbouring hns-112::TnphoA were mucoid and had altered levels of DNA supercoiling, as...
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