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Article

Pervasive homeobox gene function in the male-specific nervous system of Caenorhabditis elegans.

Development (Cambridge, England) - 15 Aug 2025

Fernandez Robert W, Digirolamo Angelo J, Valperga Giulio, Aguilar G Robert, Molina-García Laura, Kersh Rinn M, Wang Chen, Pe Karinna, Ramadan Yasmin H, Loer Curtis, Barrios Arantza, Hobert Oliver

Abstract excerpt

We explore here how neuronal cell type diversity is genetically delineated in the context of the large, but poorly studied, male-specific nervous system of the nematode Caenorhabditis elegans. Mostly during postembryonic development, the C. elegans male adds 93 male-specific neurons, falling into 25 cardinal classes, to the predominantly embryonically generated, sex-shared nervous system, comprising 294 neurons...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 40838983
DOI: 10.1242/dev.204958
PMCID: PMC12949664

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