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Article

Chromosome dosage as a life span determinant in Caenorhabiditis elegans.

Mechanisms of ageing and development - 1 Jan 2000

Hartman Phil S, Ishii Naoaki

Abstract excerpt

Caenorhabiditis elegans males live longer than hermaphrodites when cultured individually. Since hermaphrodites contain a pair of X chromosomes (XX) and males are XO (there is no Y chromosome in C. elegans), we questioned whether chromosomal differences per se might impact life span. The use of mutations in the sex-determination genes tra-1 and her-1 allowed us to uncouple sexual phenotype from the normal X...

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Identifiers

PMID: 17644160
DOI: 10.1016/j.mad.2007.06.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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