Fluctuation tests: how reliable are the estimates of mutation rates?

Abstract excerpt

Fifty one years ago, Luria and Delbrück published in Genetics a paper that was to become a classic. In it they proved, beyond all reasonable doubt, that bacteria were mutating to phage resistance long before they could have encountered any bacteriophage. Luria and Delbrück also showed how the same experimental data could be used to estimate bacterial mutation rates. Since that time and in many different contexts...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Models, Genetic
• Share to Mutation
• Share to Stochastic Processes