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Article

Genes involved in hereditary nonpolyposis colorectal carcinoma.

Anticancer research - 1 Jan 2000

Aaltonen L A, Peltomäki P

Abstract excerpt

Hereditary nonpolyposis colorectal cancer (HNPCC) (Lynch syndrome) accounts for a small proportion of the total colorectal cancer burden, yet represents the most common form of dominantly inherited colon cancer. Until recently, the diagnosis has been based on family history of colorectal and other intra-abdominal cancers. This has been problematic since chance clustering of such tumors cannot be excluded. On the...

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Source

Identifiers

PMID: 7979203

Genes

MLH1
MSH2

Provenance

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Source receipt: pubmed, retrieved 7 Sept 2026.

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