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Article

Interactive effect of two candidate genes in a disease: extension of the marker-association-segregation chi(2) method.

American journal of human genetics - 1 Nov 1994

Dizier M H, Babron M C, Clerget-Darpoux F

Abstract excerpt

For elucidating the genetic component of multifactorial diseases, it is important to investigate the effect of several factors and the possible interaction between them. In particular, for many diseases it is interesting to study the interactive effect of two genes. In this context, the marker-association-segregation chi 2 method (MASC), initially proposed to detect the involvement of a candidate gene in...

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PMID: 7977341
PMCID: PMC1918330

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INS

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