Article
Segregation analysis of non-insulin-dependent diabetes mellitus in Pima Indians: evidence for a major-gene effect.
American journal of human genetics - 1 Jul 1995
Hanson R L, Elston R C, Pettitt D J, Bennett P H, Knowler W C
Abstract excerpt
Non-insulin-dependent diabetes mellitus (NIDDM) has a high prevalence in Pima Indians. The disorder is familial, but the extent to which genetic factors are involved in its etiology is largely unknown. Segregation analysis was used to determine whether familial aggregation of NIDDM in this population could reflect the action of a single major gene. The analysis included 2,697 subjects from 653 nuclear families in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.