Article
Computing power in case-control association studies through the use of quadratic approximations: application to meta-statistics.
Annals of human genetics - 1 Mar 2007
Guedj M, Della-Chiesa E, Picard F, Nuel G
Abstract excerpt
In the framework of case-control studies many different test statistics are available to measure the association of a marker with a given disease. Nevertheless, choosing one particular statistic can lead to very different conclusions. In the absence of a consensus for this choice, a tempting option is to evaluate the power of these different statistics prior to make any decision. We review the available methods...
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