Article
The function of KGF in morphogenesis of epithelium and reepithelialization of wounds.
Science (New York, N.Y.) - 4 Nov 1994
Werner S, Smola H, Liao X, Longaker M T, Krieg T, Hofschneider P H, Williams L T
Abstract excerpt
The function of keratinocyte growth factor (KGF) in normal and wounded skin was assessed by expression of a dominant-negative KGF receptor transgene in basal keratinocytes. The skin of transgenic mice was characterized by epidermal atrophy, abnormalities in the hair follicles, and dermal hyperthi...
Topics
- Aging
- Animals
- Cell Division
- Cell Movement
- Epidermis
- Epithelial Cells
- Fibroblast Growth Factor 10
- Fibroblast Growth Factor 7
- Fibroblast Growth Factors
- Growth Substances
- Hair
- Keratinocytes
- Mice
- Mice, Transgenic
- Phenotype
- Receptor, Fibroblast Growth Factor, Type 2
- Receptors, Fibroblast Growth Factor
- Receptors, Growth Factor