Article
Beyond wavy hairs: the epidermal growth factor receptor and its ligands in skin biology and pathology.
The American journal of pathology - 1 Jul 2008
Schneider Marlon R, Werner Sabine, Paus Ralf, Wolf Eckhard
Abstract excerpt
The epidermal growth factor receptor (EGFR) network, including its seven ligands and four related receptors, represents one of the most complex signaling systems in biology. In many tissues, including the skin and its appendages (notoriously the hair follicles), its correct function is necessary for proper development and tissue homeostasis, and its deregulation rapidly results in defects in cellular...
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