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Article

Smad4 disruption accelerates keratinocyte reepithelialization in murine cutaneous wound repair.

Histochemistry and cell biology - 1 Oct 2012

Yang Leilei, Li Wenlong, Wang Shaoxia, Wang Lijuan, Li Yang, Yang Xiao, Peng Ruiyun

Abstract excerpt

Keratinocyte reepithelialization is a rate-limiting event in cutaneous wound repair, which involves the migration and proliferation of keratinocytes to cover the denuded dermal surface. Transforming growth factor-β1 (TGF-β1) has the ability to induce epithelial cell migration while inhibiting proliferation, and controversial results have been generated regarding the effect of TGF-β signaling on...

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Identifiers

PMID: 22644379
DOI: 10.1007/s00418-012-0974-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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