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Article

Betacellulin regulates hair follicle development and hair cycle induction and enhances angiogenesis in wounded skin.

The Journal of investigative dermatology - 1 May 2008

Schneider Marlon R, Antsiferova Maria, Feldmeyer Laurence, Dahlhoff Maik, Bugnon Philippe, Hasse Sybille, Paus Ralf, Wolf Eckhard, Werner Sabine

Abstract excerpt

Betacellulin (BTC) belongs to the EGF family, whose members play important roles in skin morphogenesis, homeostasis, and repair. However, the role of BTC in skin biology is still unknown. We employed transgenic mice overexpressing BTC ubiquitously to study its role in skin physiology. Immunohistochemistry revealed increased levels of BTC especially in the hair follicles and in the epidermis of transgenic animals....

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Intercellular Signaling Peptides and Proteins

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Share to Neovascularization, Physiologic

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Source

Identifiers

PMID: 17960175
DOI: 10.1038/sj.jid.5701135

Genes

BTC
EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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