Article
Thioether excretion, urinary mutagenicity, and metabolic phenotype in smokers.
Journal of toxicology and environmental health - 1 Nov 1994
Sinués B, Rueda P, Benítez J, Saenz M A, Bernal M L, Lanuza J, Alda O, Tres A, Bartolome M
Abstract excerpt
In 81 healthy individuals (51 smokers and 30 nonsmokers) biological indicators of internal exposure to electrophiles derived from tobacco smoke through metabolism were evaluated. Subgroups of smokers have been established in relation to the amount and type of tobacco smoked. Acetylator and hydrox...
Topics
- Acetylation
- Adult
- Biomarkers
- Creatinine
- Debrisoquin
- Female
- Genetic Predisposition to Disease
- Humans
- Hydroxylation
- Isoniazid
- Male
- Mutagenicity Tests
- Mutagens
- Neoplasms
- Phenotype
- Smoking
- Sulfides