Article
Studies of the pathogenesis of wild-type virus and six temperature-sensitive mutants of mouse cytomegalovirus.
Journal of medical virology - 1 Aug 1994
Furrarah A M, Sweet C
Abstract excerpt
A comparison of six temperature-sensitive (ts) mutants with the parental wild-type (wt) virus showed that, when 1-week-old BALB/c mice were inoculated intraperitoneally with 300 pfu of mouse passaged virus, the viruses could be broadly categorized into two groups. Two viruses (wt and tsm6) were l...
Topics
- Animals
- Animals, Newborn
- Herpesviridae Infections
- Immunocompromised Host
- Lethal Dose 50
- Lung
- Mice
- Mice, Inbred BALB C
- Muromegalovirus
- Mutation
- Organ Specificity
- Pneumonia, Viral
- Temperature
- Virulence
- Virus Activation
- Virus Latency
- Virus Replication