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Article

Characterization of a strain of murine cytomegalovirus which fails to grow in the salivary glands of mice.

The Journal of general virology - 1 Aug 1992

Boname J M, Chantler J K

Abstract excerpt

Characterization of a tissue culture-adapted strain of murine cytomegalovirus (MCMV), the Vancouver strain, which demonstrated altered tissue tropism in mice was undertaken to help understand the mechanism of pathogenesis of cytomegaloviruses. The Vancouver strain grew to a limited extent in the spleen but failed to grow in the salivary glands of inoculated mice. This mutation probably arose during multiple in...

Topics

3T3 Cells
Animals
Blotting, Southern
Cytomegalovirus
Female
Genome, Viral
Mice
Mice, Inbred Strains
Mutation
Restriction Mapping
Salivary Glands
Viral Plaque Assay

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Viral Proteins

Virus Replication

Source

Identifiers

PMID: 1322959
DOI: 10.1099/0022-1317-73-8-2021

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1322959-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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