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Evaluation of the replication and pathogenicity of a variant avian paramyxovirus serotype 6 in mice.

Archives of virology - 1 Oct 2017

Bui Vuong Nghia, Trinh Dai Quang, Abao Lary N B, Ozeki Yuki, Runstadler Jonathan, Nakamura Kikuyasu, Ogawa Haruko, Imai Kunitoshi

Abstract excerpt

Avian paramyxoviruses (APMVs) have been evaluated for their potential use as vaccine vectors, sparking research efforts leading to a better understanding of APMVs' replication and pathogenicity. However, within APMV serotypes, significant genetic diversity exists, and the infectivity of variant strains in mammals has not been studied. We utilized a mouse model to evaluate the pathogenicity of a variant strain of...

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PMID: 28685285
DOI: 10.1007/s00705-017-3459-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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