Article

Transport of metformin metabolites by guanidinium exporters of the Small Multidrug Resistance family

2023-08-14

Abstract excerpt

Proteins from the Small Multidrug Resistance (SMR) family are frequently associated with horizontally transferred multidrug resistance gene arrays found in bacteria from wastewater and the human-adjacent biosphere. Recent studies suggest that a subset of SMR transporters might participate in metabolism of the common pharmaceutical metformin by bacterial consortia. Here, we show that both genomic and plasmid-associ...

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Literature Corpus work: 5497d01d-64bb-5f87-bbd1-8598a004fbdc
DOI: 10.1101/2023.08.10.552832

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