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Article

Participation of lysine 516 and phenylalanine 530 of diphtheria toxin in receptor recognition.

The Journal of biological chemistry - 18 Nov 1994

Shen W H, Choe S, Eisenberg D, Collier R J

Abstract excerpt

To identify amino acid residues within diphtheria toxin that participate in receptor recognition, we made alanine replacements for each of 12 solvent-accessible residues within a loop (residues 516-530) of the toxin's R domain, which prominently extends from the main surface of the domain. Amino acid replacements were generated in an enzymatically attenuated form of the toxin (in compliance with regulations for...

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PMID: 7961874

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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