Article
Neoplastic expression in murine cells induced by halogenated hydrocarbons.
In vitro cellular & developmental biology : journal of the Tissue Culture Association - 1 Apr 1992
Schultz K, Ghosh L, Banerjee S
Abstract excerpt
The neoplastic expression in mouse embryo fibroblasts exposed to 1,2-dibromoethane and its chloroanalogue, 1,2-dichloroethane in vitro, was examined. Both substances are widely used as fumigants for carpet and upholstery, as gasoline additives, and as organic solvents. Both are known to be highly toxic, mutagenic, and carcinogenic agents. C3H10T1/2 cells treated with these haloalkanes exhibited altered morphology...
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