Article
In vitro measurement of translation accuracy of ribosomes isolated from streptomycin-resistant mutant of Streptomyces granaticolor.
Folia microbiologica - 1 Jan 1994
Weiser J, Ehrenberg M, Náprstek J
Abstract excerpt
Accuracy of activity of ribosome isolated from UV-light-induced streptomycin-resistant R-21 mutant of Streptomyces granaticolor was measured in an E. coli-derived system translating poly(U) with a high rate and accuracy. Ribosomes from the R-21 mutant strain were shown to be resistant to streptomycin and about two-fold more accurate than those from the wild type. The mutant strain was found to be resistant to...
Topics
- Drug Resistance, Microbial
- Escherichia coli
- Kinetics
- Mutation
- Protein Biosynthesis
- Ribosomes
- Streptomyces
- Streptomycin