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Article

Novel mutants of 23S RNA: characterization of functional properties.

Nucleic acids research - 25 Jun 1992

Saarma U, Remme J

Abstract excerpt

Single point mutations corresponding to the positions G2505 and G2583 have been constructed in the gene encoding E.coli 23S rRNA. These mutations were linked to the second mutation A1067 to T, known to confer resistance to thiostrepton (1). Mutant ribosomes were analyzed in vitro for their ability to direct poly(U) dependent translation, their missence error frequency and in addition their sensitivity to...

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Identifiers

PMID: 1377819
DOI: 10.1093/nar/20.12.3147
PMCID: PMC312451

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Source receipt: pubmed, retrieved 7 Sept 2026.

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