Fission yeast cut3 and cut14, members of a ubiquitous protein family, are required for chromosome condensation and segregation in mitosis.

doi:10.1002/j.1460-2075.1994.tb06821.x

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Article

Fission yeast cut3 and cut14, members of a ubiquitous protein family, are required for chromosome condensation and segregation in mitosis.

The EMBO journal - 17 Oct 1994

Saka Y, Sutani T, Yamashita Y, Saitoh S, Takeuchi M, Nakaseko Y, Yanagida M

Abstract excerpt

Fission yeast temperature-sensitive mutants cut3-477 and cut14-208 fail to condense chromosomes but small portions of the chromosomes can separate along the spindle during mitosis, producing phi-shaped chromosomes. Septation and cell division occur in the absence of normal nuclear division, causi...

Topics

Amino Acid Sequence
Animals
Bacterial Proteins
Base Sequence
Cell Nucleus
Chromosomes, Fungal
DNA Topoisomerases, Type II
Fungal Proteins
Mice
Mitosis
Molecular Sequence Data
Mutation
Phenotype
Schizosaccharomyces
Schizosaccharomyces pombe Proteins

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Identifiers

PMID: 7957061
DOI: 10.1002/j.1460-2075.1994.tb06821.x
PMCID: PMC395434

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7957061-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Sequence Homology, Amino Acid