Article
Glutamine modulates phenotype and stimulates proliferation in human colon cancer cell lines.
Cancer research - 15 Nov 1994
Turowski G A, Rashid Z, Hong F, Madri J A, Basson M D
Abstract excerpt
Glutamine supplementation has been advocated for patients requiring parenteral nutritional support. However, the direct effect of glutamine on neoplastic cells is poorly understood. We therefore investigated the effects of glutamine on the proliferation, differentiation, and cell-matrix interactions of two human colon carcinoma cell lines (Caco-2 and SW620) adapted to glutamine-free media. Doubling times were...
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