B-cell non-Hodgkin's lymphoma cell line (Karpas 1106) with complex translocation involving 18q21.3 but lacking BCL2 rearrangement and expression.

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Article

B-cell non-Hodgkin's lymphoma cell line (Karpas 1106) with complex translocation involving 18q21.3 but lacking BCL2 rearrangement and expression.

Blood - 15 Nov 1994

Nacheva E, Dyer M J, Metivier C, Jadayel D, Stranks G, Morilla R, Heward J M, Holloway T, O'Connor S, Bevan P C

Abstract excerpt

A B-cell non-Hodgkin's lymphoma (B-NHL) cell line (Karpas 1106) with an unusual three-way translocation involving 18q21.3 has been derived from a patient with mediastinal lymphoblastic B-NHL. Although conventional cytogenetics showed a derivative 18q-identical to that seen in cases with t(14;18)(q32.3;q21.3), no translocations of either chromosome 14 could be detected. Instead fluorescent in situ hybridization...

Topics

Adult
Alleles
Antigens, CD
Blotting, Northern
Cell Line
Chromosome Deletion
Chromosome Mapping
Chromosomes, Human, Pair 18
Female
Flow Cytometry
GTP-Binding Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Gene Expression

Gene Rearrangement

Genotype

Humans

Immunoglobulins

Immunophenotyping

In Situ Hybridization, Fluorescence

Source

Open in PubMed

Identifiers

PMID: 7949096

Genes

BCL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7949096-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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