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Article

Absence of p18 mutations or deletions in lymphoid malignancies.

Leukemia - 1 Feb 1996

Otsuki T, Jaffe E S, Wellmann A, Kumar S, Condron K S, Raffeld M

Abstract excerpt

p18 is a recently described cyclin-dependent kinase inhibitor (CDK-I) wih homology to p16 and p15. The latter two CDK-Is have been implicated as possible tumor suppressor genes in a wide variety of human tumors, including hematological malignancies. Because of p18's structural and functional homology to p16 and p15, we hypothesized that it may also function as a tumor suppressor gene in some lymphoid...

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PMID: 8637248

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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Absence of p18 mutations or deletions in lymphoid malignancies.PMID 8637248Read ↗

Analysis of a family of cyclin-dependent kinase inhibitors: p15/MTS2/INK4B, p16/MTS1/INK4A, and p18 genes in acute lymphoblastic leukemia of childhood.Semantic proximity Read ↗

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p16INK4A and p15INK4B gene deletions in primary leukemiasSemantic proximity Read ↗

Role of the Cyclin-Dependent Kinase 4 and 6 Inhibitor Gene Family p15, p16, p18 and p19 in Leukemia and LymphomaSemantic proximity Read ↗

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Molecular analysis of cyclin-dependent kinase inhibitors in human leukemias.Semantic proximity Read ↗

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