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Article

Transgenic copper/zinc superoxide dismutase modulates susceptibility to type I diabetes.

Proceedings of the National Academy of Sciences of the United States of America - 11 Oct 1994

Kubisch H M, Wang J, Luche R, Carlson E, Bray T M, Epstein C J, Phillips J P

Abstract excerpt

A growing body of evidence suggests that active oxygen is an important participant in the destruction of the pancreatic beta cell, which, in turn, leads to type I or insulin-dependent diabetes mellitus. Consequently, genetic factors predisposing susceptibility to insulin-dependent diabetes mellitus may include those that determine active oxygen metabolism. A direct test of this hypothesis is provided by a...

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Identifiers

PMID: 7937925
DOI: 10.1073/pnas.91.21.9956
PMCID: PMC44936

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Source receipt: pubmed, retrieved 7 Sept 2026.

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