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Article

Transgenic mice with elevated level of CuZnSOD are highly susceptible to malaria infection.

Free radical biology & medicine - 1 Jun 1998

Golenser J, Peled-Kamar M, Schwartz E, Friedman I, Groner Y, Pollack Y

Abstract excerpt

Copper/zinc superoxide dismutase (CuZnSOD) catalyses the conversion of O2.- into H2O2. Constitutive overexpression of CuZnSOD in cells and animals creates an indigenous oxidative stress that predisposes them to added insults. In this study, we used transgenic CuZnSOD (Tg-CuZnSOD) mice with elevated levels of CuZnSOD to determine whether overexpression of CuZnSOD affected the susceptibility of these mice to...

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PMID: 9641269
DOI: 10.1016/s0891-5849(98)00026-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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