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Article

Fatty Streak Formation in Fat-Fed Mice Expressing Human Copper-Zinc Superoxide Dismutase

1 Sept 1997

Abstract excerpt

Studies in vitro have shown that copper-zinc superoxide dismutase (CuZn-SOD) inhibits a number of events putatively involved in atherogenesis, including cell-mediated oxidation of LDL. To investigate whether increased activity of CuZn-SOD reduces atherogenesis in vivo, we examined diet-induced fatty streak formation in CuZn-SOD transgenic mice (n = 24) as compared with their nontransgenic littermates (n = 28)....

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Identifiers

PMID: 9327771
DOI: 10.1161/01.atv.17.9.1734

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