Article
Intracellular receptor-type transcription factor, LasR, contains a highly conserved amphipathic region which precedes the putative helix-turn-helix DNA binding motif.
Nucleic acids research - 11 Sept 1994
Fukushima J, Ishiwata T, Kurata M, You Z, Okuda K
Abstract excerpt
We have cloned and sequenced the lasR gene, which is involved in the transcriptional activation of several pathogenic factors, from Pseudomonas aeruginosa IFO3455 and PA103. These clones were predicted to be an open reading frame of 239 amino acids as reported for the PAO1 strain. There is only a...
Topics
- Amino Acid Sequence
- Bacterial Proteins
- Cloning, Molecular
- Conserved Sequence
- DNA-Binding Proteins
- Endopeptidases
- Gene Expression Regulation, Bacterial
- Genes, Bacterial
- Genetic Variation
- Helix-Loop-Helix Motifs
- Molecular Sequence Data
- Pseudomonas aeruginosa
- Sequence Analysis, DNA
- Trans-Activators