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The signaling peptide PapR is required for the activity of the quorum-sensor PlcRa in Bacillus thuringiensis.

Microbiology (Reading, England) - 1 Apr 2020

Huillet Eugénie, Bridoux Ludovic, Barboza Isabelle, Lemy Christelle, André-Leroux Gwenaëlle, Lereclus Didier

Abstract excerpt

The transcriptional regulator PlcR, its cognate cell-cell signaling heptapeptide PapR7, and the oligopeptide permease OppABCDF, required for PapR7 import, form a quorum-sensing system that controls the expression of virulence factors in Bacillus cereus and Bacillus thuringiensis species. In B. cereus strain ATCC 14579, the transcriptional regulator PlcRa activates the expression of abrB2 gene, which encodes an...

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PMID: 32067627
DOI: 10.1099/mic.0.000883

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