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Article

Properties of the Novel Proinflammatory Supergene "Intercrine" Cytokine Family

1 Apr 1991

Abstract excerpt

A family consisting of at least ten distinct novel 8-10 kd cytokines has been identified over the past 12 years. These cytokines exhibit from 20 to 45% homology in amino acid sequence, are probably all basic heparin-binding polypeptides, and have proinflammatory and reparative activities. The cDNA for these cytokines are characterized by conserved single open reading frames, typical signal sequences in the 5'...

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PMID: 1910690
DOI: 10.1146/annurev.iy.09.040191.003153

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