Article
Differential specificity for binding of retinoblastoma binding protein 2 to RB, p107, and TATA-binding protein.
Molecular and cellular biology - 1 Nov 1994
Kim Y W, Otterson G A, Kratzke R A, Coxon A B, Kaye F J
Abstract excerpt
The growth suppressor activities of the RB and p107 products are believed to be mediated by the reversible binding of a heterogeneous family of cellular proteins to a conserved T/E1A pocket domain that is present within both proteins. To study the functional role of these interactions, we examined the properties of cellular retinoblastoma binding protein 2 (RBP2) binding to RB, p107, and the related TATA-binding...
Topics
- Amino Acid Sequence
- Carrier Proteins
- Cell Cycle Proteins
- DNA-Binding Proteins
- E2F Transcription Factors
- Genes, Retinoblastoma
- Humans
- Intracellular Signaling Peptides and Proteins
- Models, Biological
- Molecular Sequence Data