Article
Estimating selection by comparing synonymous and substitutional changes.
Journal of molecular evolution - 1 Aug 1994
Smith J M
Abstract excerpt
A higher ratio of substitutional to synonymous changes in between-species than in within-species comparisons has been taken as evidence for positive selection changing amino acids. A model is presented in which a difference of this kind arises as a result of purely neutral mutations, provided tha...
Topics
- Animals
- Biological Evolution
- Drosophila
- Models, Genetic
- Mutation
- Neisseria
- Selection, Genetic
- Species Specificity