Article
Rate of sequence divergence under constant selection.
Biology direct - 21 Jan 2010
Kondrashov Alexey S, Povolotskaya Inna S, Ivankov Dmitry N, Kondrashov Fyodor A
Abstract excerpt
BACKGROUND: Divergence of two independently evolving sequences that originated from a common ancestor can be described by two parameters, the asymptotic level of divergence E and the rate r at which this level of divergence is approached. Constant negative selection impedes allele replacements and, therefore, is routinely assumed to decelerate sequence divergence. However, its impact on E and on r has not been...
Topics
- Alleles
- Base Sequence
- Genetic Loci
- Genetic Variation
- Mutation
- Selection, Genetic
