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Article

The c-myc coding region determinant-binding protein: a member of a family of KH domain RNA-binding proteins

1 Nov 1998

Abstract excerpt

The half-life of c- myc mRNA is regulated when cells change their growth rates or differentiate. Two regions within c- myc mRNA determine its short half-life. One is in the 3'-untranslated region, the other is in the coding region. A cytoplasmic protein, the coding region determinant-binding protein (CRD-BP), binds in vitro to the c- myc coding region instability determinant. We have proposed that the CRD-BP,...

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PMID: 9801297
DOI: 10.1093/nar/26.22.5036

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