Article
Amyloid precursor protein mRNA stability is controlled by a 29-base element in the 3'-untranslated region.
The Journal of biological chemistry - 30 Sept 1994
Zaidi S H, Malter J S
Abstract excerpt
In the accompanying paper (Zaidi, S. H. E., Denman, R., and Malter, J. S. (1994) J. Biol. Chem. 269, 24000-24006) we demonstrate that in tumor and normal cells, multiple cytosolic proteins interact with a 29-base sequence in the 3'-untranslated region of amyloid precursor protein (APP) mRNA. These data suggested that APP gene expression may be modulated by regulated APP mRNA decay. We have investigated this...
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