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Article

Conversion of a mesodermalizing molecule, the Xenopus Brachyury gene, into a neuralizing factor.

Genes & development - 15 Apr 1994

Rao Y

Abstract excerpt

It has been shown previously that a Xenopus homolog of the mouse gene Brachyury, Xbra, can initiate mesodermal differentiation. Here, I report that a Xbra mutant truncated at the carboxyl terminus, B304, has lost the mesodermalizing activity and can block the activity of the wild-type Xbra. Injection of B304 mRNA led to formation of neural structures in animal cap explants. Examination of molecular markers in...

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Identifiers

PMID: 7926778
DOI: 10.1101/gad.8.8.939

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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