Article
Disruption of BMP signals in embryonic Xenopus ectoderm leads to direct neural induction.
Genes & development - 1 Dec 1995
Hawley S H, Wünnenberg-Stapleton K, Hashimoto C, Laurent M N, Watabe T, Blumberg B W, Cho K W
Abstract excerpt
Bone morphogenetic proteins (BMPs), which have been implicated in the patterning of mesoderm, are members of the transforming growth factor-beta (TGF-beta) superfamily. We have investigated the roles of Xenopus BMP-7 (XBMP-7) and BMP-4 (XBMP-4), and activin (another TGF-beta-related molecule) in...
Topics
- Activins
- Animals
- Base Sequence
- Bone Morphogenetic Protein 7
- Bone Morphogenetic Proteins
- Ectoderm
- Embryonic Induction
- Gastrula
- Gene Expression Regulation, Developmental
- Inhibins
- Mesoderm
- Molecular Sequence Data
- Mutation
- Neural Pathways
- Oocytes
- Proteins
- Signal Transduction
- Transforming Growth Factor beta