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Article

Disruption of BMP signals in embryonic Xenopus ectoderm leads to direct neural induction.

Genes & development - 1 Dec 1995

Hawley S H, Wünnenberg-Stapleton K, Hashimoto C, Laurent M N, Watabe T, Blumberg B W, Cho K W

Abstract excerpt

Bone morphogenetic proteins (BMPs), which have been implicated in the patterning of mesoderm, are members of the transforming growth factor-beta (TGF-beta) superfamily. We have investigated the roles of Xenopus BMP-7 (XBMP-7) and BMP-4 (XBMP-4), and activin (another TGF-beta-related molecule) in early development by generating dominant-negative versions of these growth factors. Mutations were generated by...

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Identifiers

PMID: 7498789
DOI: 10.1101/gad.9.23.2923

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Disruption of BMP signals in embryonic Xenopus ectoderm leads to direct neural induction.PMID 7498789Read ↗

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Endogenous and ectopic expression of noggin suggests a conserved mechanism for regulation of BMP function during limb and somite patterning.Semantic proximity Read ↗

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XBMP-1B (Xtld), a Xenopus homolog of dorso-ventral polarity gene in Drosophila, modifies tissue phenotypes of ventral explants.Semantic proximity Read ↗

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