The Doa locus encodes a member of a new protein kinase family and is essential for eye and embryonic development in Drosophila melanogaster.

doi:10.1101/gad.8.10.1160

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Article

The Doa locus encodes a member of a new protein kinase family and is essential for eye and embryonic development in Drosophila melanogaster.

Genes & development - 15 May 1994

Yun B, Farkas R, Lee K, Rabinow L

Abstract excerpt

Mutations at the Darkener of apricot (Doa) locus of Drosophila cause roughened eyes and increase transcript accumulation from the retrotransposon copia up to fourfold. Cloning of the gene and sequencing of cDNAs reveals that it encodes a putative serine/threonine protein kinase. Sequence data bas...

Topics

Amino Acid Sequence
Animals
Base Sequence
Cloning, Molecular
Drosophila Proteins
Drosophila melanogaster
Eye
Female
Gene Expression Regulation, Developmental
Genes, Insect
Genes, Lethal
Genotype
Male
Molecular Sequence Data
Phosphorylation
Protein Kinases
Protein Serine-Threonine Kinases
RNA, Messenger

Source

Open in PubMed

Identifiers

PMID: 7926721
DOI: 10.1101/gad.8.10.1160

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7926721-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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