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Article

Natural alleles at the Doa locus underpin evolutionary changes in Drosophila lifespan and fecundity.

Proceedings. Biological sciences - 9 Nov 2022

Hoedjes Katja M, Kostic Hristina, Keller Laurent, Flatt Thomas

Abstract excerpt

'Evolve and resequence' (E&R) studies in Drosophila melanogaster have identified many candidate loci underlying the evolution of ageing and life history, but experiments that validate the effects of such candidates remain rare. In a recent E&R study we have identified several alleles of the LAMMER kinase Darkener of apricot (Doa) as candidates for evolutionary changes in lifespan and fecundity. Here, we use two...

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Identifiers

PMID: 36350205
DOI: 10.1098/rspb.2022.1989
PMCID: PMC9653240

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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